产品货号：
Z34401
中文名称：
Mesothelin/MSLN抗体
英文名称：
Anti-Mesothelin/MSLN Antibody (Clone#MN-1)
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Mesothelin/MSLN Antibody (Clone#MN-1) |
| 指标别名 | mesothelin;MPF;SMRP;MSLN |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | IHC,SDS-PAGE,WB |
| 基因名称 | MSLN |
| 克隆号 | MN-1 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG2a |
| 免疫原 | This antibody was produced in mesothelin-deficient mice by immunizations with plasmid cDNA encoding human MSLN full length protein followed by a single boost of a recombinant human mesothelin-Fc fusion protein. |
| 计算分子量 | 69kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This antibody is directed against human mesothelin protein.This product was purified from tissue culture supernatant fluid by Protein A chromatography.Cross-reactivity with homologues from other sources has not been tested. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Anti Mesothelin Antibody recognizes Mesothelin that is a glycosyl-phosphatidylinositol每anchored glycoprotein present on the cell surface of various human solid tumors.The mesothelin (MSLN) gene encodes a 71-kDa precursor protein that is processed to a 40-kDa glycosylphosphatidylinositol每anchored protein that composes the mature portion and an NH2 terminal 31-kDa fragment called megakaryocyte-potentiating factor that is released from the cell.Mesothelin is a tumor differentiation antigen present at low levels on a restricted set of normal adult tissues,such as mesothelium,but aberrantly over expressed in mesotheliomas,ovarian,and pancreatic cancers.The biological functions of mesothelin remain elusive.A recent study showed that mesothelin binds to MUC16/CA125,and that this interaction mediates cell adhesion,suggesting that there may be an important role for MUC16/CA125 and mesothelin in the metastatic spread of ovarian cancer. |
| Uniprot ID | Q13421 |
| 基因名全称 | Mesothelin |
| 推荐稀释比 | ELISA:1:10,000 - 1:50,000 Flow Cytometry:User Optimized IHC:1:100 WB:1:1,000 |
相关搜索：Mesothelin/MSLN抗体，Mesothelin抗体，MSLN单抗，Anti-Mesothelin/MSLN Antibody (Clone#MN-1)